( Chemical Engineering : Operations , Solid-solid operations )
Other approaches combine these chemical and physical methods of disruption, such as
lysozyme treatment followed by sonication or pressure treatment, to maximize cell disruption and protein release.
During cell disruption, small bioproducts are usually secreted from the cell, making the first separation
step reasonably straightforward.
Cell disruption is when a biological material becomes smaller to release proteins and enzymes.
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