1. singular noun The negation of something is its complete opposite or something which destroys it or makes it lose its effect. [formal] [+ of] ⇒ Unintelligible legislation is the negation of the rule of law and of parliamentary democracy. 2. uncountable noun Negation is disagreement, refusal, or denial. [formal] ⇒ The editor grimaced, gesturing in negation. ⇒ Isabella shook her head, but in bewilderment, not negation.
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